On May 26, the von Liebig Entrepreneurism Center successfully completed its third year and seventh Cohort as an NSF I-Corps site. To celebrate, the Center threw a reception for all the students, faculty, and mentors who have participated, ending the night with presentations from Spring Quarter’s 12 teams. During the final presentations, teams presented their ideas, target markets, and lessons learned from customer interviews conducted throughout the quarter.

Each of the mentors ranked the presenting teams categories of progress throughout the program, as well as quality of presentations. Each and every mentor believes that the teams have developed significantly from their initial idea pitches to their final presentations.

For example, the idea for Catalyst Technologies was initially developed in India.  Through customer discovery and market research, Lenord Melvix, the Entrepreneurial Lead, pivoted his focus from Indian to small American hydroponic farmers who were interested in seeing how his solutions could significantly cut their operation costs.

Dr. Seth Alexander of GenTag Solutions identified that designing multiple "all-in-one kits" that allow technicians to tag and capture RNA are much more useful and potentially profitable than his initial offering of a "do-it-yourself" method for clinical and academic researchers. He was able to gather this crucial information through the customer discovery process, an important tactic taught by mentors at the Center.

Armando Armillo of Saros created unique 3D Printers for community maker spaces and individual hobbyists. Through the customer discovery process,  these customer segments revealed the need for a niche quality of 3D printing between high-cost industry grade and the slower, lower-cost consumer grade 3D printing.

Saharnaz Baghdadchi of Singular Imaging, a team from the Phase II group, is developing a single-pixel imaging microscope that reduces the time and cost of stem cell tissue sample processing.  Through customer discovery, researchers confirmed that a beneficial application of the microscope is its high-definition quality, providing images of greater depth for brain imaging research.

Over the past three years, the von Liebig Center (vLC) has trained approximately 100 teams (250 student and faculty participants) in the process of starting a company using the customer discovery process and lean startup methodology.  The two-phase program has resulted in over 2,780 customer interviews conducted, and 19 teams have since filed patents, 44 teams have created prototypes, and 9 teams have gone to the NSF I-Corps Teams (National) program.

According to a survey sent out to the teams, participants revealed that the best part of the (vLC) I-Corps program was the focus on mentor relationships, the cultivation of the entrepreneurial mindset, the understanding the customer discovery process, and enhanced presentation skills.

“The best part of the I-Corps program was going through the process of determining the value of your technology,” says Dustin Fraley of the HeatSeq project. “Great framework for developing a business plan and justifying why your technology is needed through potential user interviews,” Fraley said, commenting that it was an invaluable experience.

Beyond commercialization of technology, the von Liebig Center also hopes to impart and encourage an entrepreneurial mindset in students, faculty, and staff that will help in job searches, identifying other areas of research that are translatable, and writing more competitive grant proposals. This is in line with the vision of Don Millard, the Deputy Division Director of the Engineering Education and Centers (EEC) Division at the National Science Foundation. Millard has held this philosophy since the NSF I-Corps program was founded. Millard attended the Institute of the Global Entrepreneur launch on June 2nd and met with the Center about the strong outcomes UC San Diego’s NSF I-Corps site has produced.

“The best thing I learned was entrepreneur-like thinking. I'm currently looking into other potentially translatable technologies in my lab with the mindset imparted to me by the I-Corps program,” says Wangzhong Sheng, from the AMDepot project.

The NSF I-Corps program will be offered again in Fall 2016. Applications are open and teams will be selected in September. Click here to apply!

As a tribute to the success of NSF von Liebig Center, 5 out of the 8 finalists in the UCSD Entrepreneur Challenge -- NanoVR, Pain Measurement Technologies, Clip Diagnostics, Locana, and Genrix – had participated in the vLC I-Corps program and were awarded funds towards their projects by placing in the top 3 of their track.

Read more about the winners here, and take a look through Priya Bisarya’s experience here. 

Illuminating Your Movement: Entrepreneur Showcases Lighting Company at Institute for Global Entrepreneur Launch Event

Dancer and handstand instructor Tammuz Dubnov graduated from UC Berkeley at the age of 18; now at the age of 21, he runs a successful lighting company, all while working on his masters degree in materials science at UC San Diego.

Zuzor, the company Dubnov started, illuminates your movement using a sensor (like Xbox Kinect) to capture your movement, project it onto a screen, and overlay beautiful graphics like the ones in the video above.

Dubnov was present at the launch event for the new Institute for the Global Entrepreneur at UC San Diego June 2 to showcase his technology. The Institute is a collaboration between the UC San Diego Jacobs School of Engineering and Rady School of Management and is dedicated to training engineering leaders and translating university discoveries to the market. Dubnov participated in the NSF I-Corps program at UC San Diego, run by the von Liebig Entrepreneurism Center, which is a part of the new institute.

To learn more about the Institute for the Global Entrepreneur, go to IGE.ucsd.edu.

UC San Diego Startup Invited to First-Ever White House Demo Day

Cocoon Cam

Wearless Tech, Inc., a San Francisco/San Diego startup with its roots in the University of California, San Diego’s Computer Science and Engineering department, was invited to showcase their first product – a wellness video baby monitor – in the first-ever White House Demo Day on August 4, 2015. The event was hosted by President Obama and brought in innovators from across the country, including the co-founders of Wearless Tech, Rubi Sanchez, Siva Nattamai, and UC San Diego computer science alumnus Pavan Kumar Pavagada Nagaraja, MS ‘15.

Nattamai and Sanchez first met at a hackathon where they had the idea for a baby monitor that could detect a baby’s heartbeat without any wearable sensors attached. After interviewing a number of parents, the pair realized that the need was greater – a monitor that can non-invasively detect the baby’s heart rate, respiration and temperature and then send an alert when something isn’t right. That’s when UC San Diego computer science and engineering graduate student Pavan Kumar, now an alumnus and currently employed as researcher in the Computer Science and Engineering Department, joined the team as a software developer. Together, the three co-founded Wearless Tech, Inc. and began work on what would become their first product – Cocoon Cam.

“Cocoon Cam is unique in that it is completely non-invasive,” said Kumar. “The hardware consists of a video camera with a passive infrared sensor, meaning that unlike other technologies, no microwaves are emitted. Instead, it gathers data from the camera and sends it to the cloud, where software analyzes the video.”

Using the latest advances in computer vision, machine learning, and Infrared (IR), Cocoon Cam is able to detect a baby's presence and positioning, making it the first video baby monitor that can transmit live information about a baby's safety and activity without invasive wearable technology

Once it receives the video feed, the software amplifies and quantifies the color changes in the baby’s skin and the movement of the baby’s chest. From there, a notification is sent to the parents’ smartphone app alerting them to changes in the baby’s heart rate, respiration and temperature.

Cocoon Cam can be pre-ordered beginning in October.

Wearless Tech is currently continuing its collaboration with UC San Diego and Weibel to conduct field patient studies in both clinical and in-home environments. In the future, the company plans to develop intelligent video camera systems that provide continuous, non-contact and non-invasive vital sign monitoring for Neonatal and Pediatric Intensive Care Units (NICUs/PICUs) and Emergency Rooms (ERs). The technology promises to reduce false alarms and alarm fatigue in critical care environments, and the team plans to test its efficacy through an NSF grant for which they applied in collaboration with UC San Diego’s Computer Science and Engineering and Pediatrics departments in early summer 2015. Other areas under development include post-surgery and eldercare monitoring as well as enhanced screening for security applications.

Interested in supporting Cocoon Cam? Visit https://www.cocooncam.com.

Read about Wearless Tech's journey to the White House here.

von Liebig I-Corps Program Expands and Continues At Full Speed

Each quarter, the von Liebig Entrepreneurism Center’s I-Corps program continues at full speed, connecting students with the Center’s business and technology mentors and helping teams get ready to launch their products into the marketplace. During the 2014-2015 academic school year, the program had over 60 applicants express interest. 31 teams completed Phase I, offered in the Fall and Winter, and 25 teams completed Phase II, offered in the Winter and Spring. After graduating the von Liebig I-Corps program, two teams from the 2014-2015 cohort were accepted into the National I-Corps Program in Washington D.C., while others demonstrated their skills by competing in campus-wide, statewide and national competitions and taking home cash prizes and awards.

The Center is excited to see the I-Corps program expand and very proud of their teams and all that they have accomplished. The von Liebig I-Corps program is modeled after the National Science Foundation’s Innovation Corps program, with two phases for teams to develop their business models. To offer flexibility and more mentoring to their students, the Center allows the accepted teams to decide whether they want to continue onto Phase II after completing Phase I of the program.

The von Liebig Entrepreneurism Center gladly welcomes UC San Diego students, staff and alums to apply to participate as a Phase I team in its the I-Corps program in the fall and join our network of mentors and entrepreneurs. While the hard work does not end here, we know it won’t be long until this cohort’s projects and ideas hit the market. Until then, we’ll let you take a peek at what many of our teams have been working on.

The Cocoon Cam team and mentor
Dennis Abremski completed the National
I-Corps Program in Washington, D.C.

Wearless Tech Inc., Intraocular Pressure Sensor, AMDepot, HeatSeq, Meego, Wastelights, Gyroscopic Ocean Wave Energy Converter (GOWEC), PlasmaCaps, 3D Organ on a Chip, EMERES: Cyber System for Structural Health Monitoring, Data Intelligence, Enzyme Diagnostics, MuDetect, Pressure Sensitive Touchscreen, Open Topography, SciCrunch and FRET Biosensors became experts at developing business models and are well-equipped with customer insight, mentor advice and industry connections to aid them in their next steps forward. These teams have completed the both phases of the program for a combined sixteen weeks of instruction and mentoring.

Team members Pavan Kumar Pavagada Nagaraja, Sivakumar Nattamai and Rubi Sanchez founded Wearless Tech Inc,. a company that further developed their project Cocoon Cam: Wearless Smart Baby Monitor in the I-Corps program with mentor Dennis Abremski, VP of SoCal EED, Inc. Cocoon Cam is a wearless (non-contact), network-connected baby monitor designed for parents looking for a simple, secure way to monitor their newborns. The device uses machine vision to measure heart and respiratory rate and infrared sensors to detect skin temperature. After completing the von Liebig I-Corps Program, the team went on to complete the National I-Corps Program in Washington, D.C.

Oculux team took 2nd place at this year's Entrepreneur Challenge,
AMDepot (not pictured) took home 4th place.

Mechanical Engineering graduate students Alex Phan, Yung Seo and Ben Suen of the Oculux (formerly Intraocular Pressure Sensor) team developed a novel implantable pressure sensor that allows continuous monitoring and enables physicians to personalize treatment plans for patients and better preserve their vision. The team explained that glaucoma is an incurable eye disease that affects 60 million people worldwide, and the lack of frequent eye pressure measurement prevents successful treatments and increase in total blindness. Oculux took home second prize at Entrepreneur Challenge this year and was also recently accepted into the Fall 2016 Cohort of the National I-Corps Program.

Mechanical engineer Wangzhong Sheng and nanoengineer Viet Anh Nguyen Huu of AMDepot developed a drug delivery vehicle that releases therapeutic amounts through a single injection of a depot that is activated by biologically benign flashes of light. AMDepot’s method reduces the frequency of injections needed, as well as allows noninvasively controlled dosing. AMDepot explained that the estimated global healthcare cost for eye-related diseases is well over $250 billion and that one of the most severe diseases, the wet-form of age-related macular degeneration (wet AMD) affects 2 million Americans and can lead to severe and sudden loss of vision. The current treatment for AMD requires monthly or bi-monthly injections of drugs into the eye, which can lead to complications with each injection. AMDepot also took home fourth prize at this year's Entrepreneur Challenge.

HeatSeq team members Dustin Fraley and Stephanie Fraley developed an integrative technology that allows for rapid, automated, and highly accurate DNA profiling from a single precious clinical sample. “We are developing this technology for use in personalized medicine, where there is a need for more comprehensive molecular analysis of DNA for profiling diseases and drug efficiency,” wrote the team members.

Meego team members Delara Fadavi, Aditi Gupta, Ian McNair, Sammie Wang, Oscar Guerrero and Katya Grishna explain that stolen laptops, in the United States alone, account for $2.1 billion in losses annually and that most thefts occur in public places or during travel. The team aims to deter laptop theft through their small, mountable portable device that will sound an alarm when unanticipated motion is detected and notify owners via mobile alert if their Meego has been activated.

The Wastelights team took the hard reality that the world has an abundance of waste, but not enough electricity, and served up a solution. Team members Joyce Sunday and Nitya Timalsina developed their second prototype of a device that eliminates waste by converting it into electricity and biochar. Wastelights’ constructed prototype is able to reliably provide energy and eliminate waste without combustion at low cost and maintenance. During the program, Wastelights was able to generate transnational interest and conduct interviews from abroad.

Oscar Rios and Ardavan Amini of Gyroscopic Ocean Wave Energy Converter (GOWEC) address the need for clean and efficient power generation in a wide range of markets through the development of their wave energy converter that utilizes gyroscopic principles. The team explains: “the world currently uses approximately 15 trillion kWh of electricity per annum, representing just 0.02 percent of the energy contained throughout the world’s oceans.”

Graduate student Rajaram Narayanan and Prabhakar Bandaru, Ph.D. of the PlasmaCaps team designed a powerful energy technology that improves energy density capacitors. PlasmaCaps was accepted into the accelerated National I-Corps program in Washington D.C. and plans to continue improving their design. During the program, the team was mentored by Kai Wenk-Wolff, M.B.A., conducted customers interviews and incorporated feedback into their redesign.

The 3D Organ on a Chip team recognized that too many drugs pass cell based testing on to animal testing and that pharmaceutical companies spend $1-3 billion on each drug when bringing them to market. After conducting 23 customer interviews, team members Aereas Aung, Gaurav Agrawal, Ivneet Bhullar and Han Liang Lim identified a specific market niche and verified a need for their platform to reduce the time and cost of preclinical studies.

Structural Engineering Ph.D. candidate Hamed Ebrahimian presented EMERES: Cyber System for Structural Health Monitoring, his low cost system for rapid health monitoring and damage analysis of offshore platforms. Ebrahimian explained the need for their technology, noting that platform structures age, are expensive and often fail. His automated resident monitoring system would replace inspection process of platform structures, while its mechanic space model is trained to pinpoint damage, location and other detailed information that inspections cannot provide.

Siarhei Vishniakou, Cooper Levy and Conor Riley make up the Pressure Sensitive Touchscreen team who want to expand traditional touchscreens’ limited capabilities. “Most touchscreens can only detect location, and cannot sense how hard the user actually pressed” explained the team. Their product is a touchscreen that can determine the intensity of a user press for music, medical and gaming applications. During the program, the Pressure Sensitive Touchscreen team conducted over 20 customer interviews, saw a great fit in the market and found their biggest competitor.

Augusta Modestino, Ph.D. and Ph.D. candidate Elaine Skowronski make up the Enzyme Diagnostics team that hopes to fill the gap within in vitro diagnostics, so that data can translate from high-throughput volume labs to point of care systems. During their presentation, the team explained that diagnostics are the silent champion of healthcare and that there is a need for better result comparisons for in and out patients.

The Data Intelligence team from UC San Diego’s Math Department created a novel technique for data extraction, allowing users to merge databases and cross reference data for improved predictions. During the program, team members David Meyer, David Rideout, Asif Shakeel gained insight into how and where their product would fit best in the market.  

Matt Walsh and Aric Jonejah, Ph.D. of the MuDetect team created a simplified analysis system that only detects relevant mutations to reduce both cost and supply of clinics and labs. During the program, the team learned how to identify and target customer segments and define their value proposition.

OpenTopography team members Vishu Nandigam and Chris Crosby developed an improved high resolution dataset and software tool for processing data using a cloud hosted solution with web based software and an interactive map interface. Their workflow-based system provides a significantly more efficient solution for distribution and processing of massive datasets.

The SciCrunch wants to accelerate biomedical research by means of an open access “data ocean.” Team members Anita Bandrowski, Ph.D., Jeffrey Grethe, Ph.D., Maryann Martone, Ph.D. and Andrea de Souza, MBA want to develop a platform that makes data accessible easily findable, interoperable and reusable. Throughout the program, the team conducted customer interviews that helped them identify the market’s segments and customers and analyze its competitors.