Showing posts with label NIH. Show all posts
Showing posts with label NIH. Show all posts

Friday, May 13, 2016

#ILookLikeAnEngineer: Mary Graves

Meet Mary, a graduating chemical engineer who is not only a MARC U-STAR Awardee, but also a Gordon Scholar and has interned at the National Institutes of Health in neuropharmacology.

Mary Graves
Chemical Engineering
Expected graduation date: June 2016



Why chemical engineering at UC San Diego?
Let me start by tell you why I chose to study at UC San Diego. During my senior year in high school, I was watching a program on KPBS about the science behind cereals, and UC San Diego chemical engineers who made Fruit Loops could measure and know how much sugar was on each loop. I was amazed but the detail that went into each piece of cereal and by the chemical engineers who understood every aspect. Chemical engineering has a plethora of applications and I wanted the knowledge that came with it, such as fluid mechanics which explains the laws governing all flow.

I thought it was amazing and wanted to be involved in food because of it. But then, I also have an interest in biomedical research because my grandmother died of a preventable cause when I was a kid. In addition, my family struggled with substance abuse and medical disorders, so I’ve gravitated toward research questions that will help us better understand why these things happen.


What was your transition into UC San Diego like as a transfer student?
Transitioning from community college was difficult. When I came to UC San Diego, it was a lot more competitive and I was no longer the best at what I wanted to do. Everyone else was the best, too - and you have to be, to get into the engineering program here. It did push me to work harder but sometimes that was not enough. I found my outlet through extracurricular activities.

Can you describe your involvement in different organizations here at UC San Diego?
During my time at UCSD I was part of the Academic Enrichment Program (AEP). I was awarded the competitive MARC Honor fellowship which funded research on and off campus and travel for two years. I presented my research at the 2014 SACNAS conference in San Antonio, TX. While at the conference I met the director of summer internships for the National Institute of Neurological Disorders and Stroke. I explained my research interests, long term goals, the research I was presenting and desire to participate in the program. The program has a less than 10% acceptance rate so I did not think I would get in. However, I was accepted. It was a great experience and I would recommend NIH and DC to everyone.

The Gordon scholars were a great leadership development program. It prepared me to be an effective and understanding leader through team building exercises and discussions.

Being an AICHE officer allowed me to use the skills from the Gordon program. I coordinated events with upwards of 300 participants in an effort to give back to the community and showcase the science behind chemical engineering through demonstrations.


What are your career goals?
I want to go into academia, but there isn’t a lot of flexibility unless you get the grants for it. I’ve done modeling behavior with drugs, such as cocaine and now I’m working with neural modulations. We are looking for correlations to see if people can recall memories. I’m also interested in neuroscience at the intersection between neuroscience and pharmaceuticals. I interned at a neuropharmacology lab for about a year and a half. I was the National Institutes of Health (NIH), working on and designing new drugs.


What are three things that make you an individual?

  1. I really like hot sauce. Louisiana hot sauce. JalapeƱos, habaneros, serranos. Every hot sauce.
  2. I’m a really good listener.
  3. I have good tenacity and persistence, which is what makes me a good engineer. Engineering is where you learn how to take defeat.   

Friday, July 18, 2014

Juan C. Lasheras Joins NIH MABS Study Section

Distinguished Professor Juan C. Lasheras from UC San Diego has accepted an invitation from the U.S. National Institutes of Health (NIH) to serve as a member of the Modeling and Analysis of Biological Systems Study Section, which reviews grant applications for scientific merit as a part of the NIH Center for Scientific Review.

The Modeling and Analysis of Biological Systems Study Section (MABS) reviews NIH grant applications concerned with the development of modeling / enabling technologies for understanding the complexity of biological systems. The scope of these systems ranges from molecular, to supra-molecular, to genes, to organelles, to cellular, to tissue and to organ level studies.

In March 2014, Lasheras and a team of biologists and engineers from UC San Diego published a paper in the Journal of Cell Biology (JCB) in which they reported their discovery that white blood cells move to inflamed sites by walking in a stepwise manner. The cells, the researchers found, periodically form and break adhesions mainly under two “feet,” and generate the traction forces that propel them forward by the coordinated action of contractile proteins.

Their discovery, which was highlighted on the cover of the March 17 issue of JCB, is an important advance toward developing new pharmacological strategies to treat chronic inflammatory diseases such as arthritis, irritable bowel syndrome, Type 1 diabetes, and multiple sclerosis.


Modeling and Analysis of Biological Systems

Tools developed by grants funded by the NIH Modeling and Analysis of Biological Systems study section are characteristically applied to further understanding of interactions and integrations through levels and scales and the emergence of patterns that help to explain system behavior.

Members are selected on the basis of their demonstrated competence and achievement in their scientific discipline as evidenced by the quality of research accomplishments, publications in scientific journals, and other significant scientific activities, achievements and honors. 

Professor Lasheras, for example, holds the Stanford S. & Beverly P. Penner Professor in Engineering or Applied Science endowed chair at the UC San Diego Jacobs School of Engineering. A member of the National Academy of Engineering, Lasheras is a faculty member in the Department of Mechanical and Aerospace Engineering at the Jacobs School.

Professor Lashers serves as Director of the Center for Medical Devices and Technology, part of the Institute for Engineering in Medicine at UC San Diego. He is a Faculty Director of the Medical Device Engineering executive master’s degree program at the UC San Diego Jacobs School of Engineering.


Lasheras joins UC San Diego bioengineering professor Andrew McCulloch on the 16-person Modeling and Analysis of Biological Systems Study Section. UC San Diego is the only university with more than one professor on this NIH study section.